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Fragment-based lead discoveryHigh-throughput screeningDrug developmentHigh-content screeningProcess chemistryDrug discoveryLead compoundMolecular modificationDruggabilityDna-encoded chemical libraryPharmaceutical formulationPrecursor chemicalsBottom-up proteomicsLipophilic efficiencySemisynthesisSolid-phase synthesisMedicinal chemistryShotgun proteomicsGenome miningPharmaceuticsTitrationChemical testReaction intermediateDerivatizationBioanalysisBioprospectingScreeningMetabolomicsSolid-phase extractionMass spectrometry imagingTotal synthesisGas chromatographyDrug repositioningChemical structureBioassayQualitative inorganic analysisOperando spectroscopyPharmaceutical manufacturingAnalytical techniqueSize-exclusion chromatographyBioactive compoundSpectroelectrochemistryChemical synthesisLow-energy ion scatteringImmunoassayElectron-transfer dissociationMicroanalysisAnalyteSplit and pool synthesisDe novo peptide sequencingThermal shift assayMolecular probeFast protein liquid chromatographyTransition state analogColumn chromatographyAlanine scanningElectrochemical stripping analysisAffinity chromatographySample preparationIsopropylbenzylamineDrug reference standardDynamic covalent chemistryMetabolic engineeringOligonucleotide synthesisDruglikenessClick chemistryGel permeation chromatographyReagentDrug testSmall-angle neutron scatteringPeptide synthesisDispersion polymerizationPhase-transfer catalystCollision-induced dissociationSecondary ion mass spectrometryChromatographyNanoparticle drug deliveryMechanism of actionApplied spectroscopyProtecting groupBiotechnologyCombustion analysisBioisostereChemical changeBiopharmaceuticalSmall moleculeClonogenic assayElectron ionizationIsomerizationMutation breedingSolid-state chemistrySynthetic genomicsPharmacyForensic toxicologyChemical transport reactionIon mobility spectrometryTogni reagent iiDe novo synthesisBiomarker discoveryProximity labeling